L-655,240
- CAS NO.：103253-15-2
- Empirical Formula: C21H21ClFNO2
- Molecular Weight: 373.85
- MDL number: MFCD04040005
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24
What is L-655,240?
The Uses of L-655,240
L-655,240 is a selective and potent thromboxane and prostaglandin endoperoxide antagonist. Also used in the structure-based and ligand-based drug design for microsomal prostaglandins E synthase-1 inhibitors.
What are the applications of Application
L-655,240 is a selective and potent thromboxane and prostaglandin endoperoxide antagonist
Definition
ChEBI: 3-[1-[(4-chlorophenyl)methyl]-5-fluoro-3-methyl-2-indolyl]-2,2-dimethylpropanoic acid is a methylindole.
Biological Activity
Potent and selective thromboxane A 2 /prostaglandin endoperoxide receptor antagonist. pA 2 values are 8-8.4 in guinea pig smooth muscle; IC 50 = 7 nM for inhibition of human platelet aggregation. Orally active in vivo .
Properties of L-655,240
| Boiling point: | 548.7±50.0 °C(Predicted) |
| Density | 1.22±0.1 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | DMSO: 30 mg/mL |
| form | solid |
| pka | 4.82±0.10(Predicted) |
| color | off-white |
Safety information for L-655,240
Computed Descriptors for L-655,240
New Products
Dexamethasone Sodium Phosphate p-Anisaldehyde m-Tolualdehyde 2-Bromobenzaldehyde 4-Fluorobenzaldehyde 1-Propyl-4-piperidone 3-Amino-3-(3-fluorophenyl)propanoic acid Raloxifene EP Impurity D N-Nitroso Nortriptyline Nitroso Irbesartan 2-(p-Tolyl)acetaldehyde Sulfonic acid Impurity 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one 5-Chloro-2-Methoxy-4-Picoline 2-Amino-6-nitrobenzoic Acid (6-Nitroanthranilic acid) Cis-3,5 Diacetoxy-1-cyclopentene 3-Bromo-2-Methoxy-4-Methylpyridine 2-Amino-5-Chloro-3-Nitro-6-picoline 3-Methoxy-5-methylpyrazin-2-amine Pentachlorobenzonitrile Budesonide Nicotinic acid RAPAMYCIN Alpha CyclodextrinRelated products of tetrahydrofuran
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