KRN383
- CAS NO.：919767-02-5
- Empirical Formula: C17H17N3O4
- Molecular Weight: 327.33
- MDL number: MFCD28138417
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-05 11:31:08
What is KRN383?
Description
KRN383 also inhibited the proliferation of the ITD-positive cell lines with IC(50) values of < or =2.9 nM. A single oral administration of 80 mg/kg of KRN383 eradicated ITD-positive xenograft tumors in nude mice and prolonged the survival of SCID mice carrying ITD-positive AML cells. The effectiveness of a single oral dose of KRN383 suggests that it has the potential to be used in a wide variety of clinical regimens, including multicycle and combination therapies.
Properties of KRN383
| Boiling point: | 539.9±50.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| pka | 6.18±0.40(Predicted) |
Safety information for KRN383
Computed Descriptors for KRN383
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