KP1019
- CAS NO.:124875-20-3
- Empirical Formula: C14H12Cl4N4Ru.C7H6N2.H
- Molecular Weight: 598.29
- MDL number: MFCD00892953
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-18 09:52:05
What is KP1019?
Pharmaceutical Applications
KP1019 is active against
primary cancers, whereas NAMI-A is active against metastasis, secondary tumours that have moved to other
areas. The treatment of metastasis is currently an area where improvement is urgently needed.KP1019, trans-[tetrachloro-bis(1H-indazole)ruthenate(III)], was tested in phase I clinical trials as a possible
treatment option against colon cancer. Administered doses ranged from 25 to 600 mg twice weekly,
and no significant side effects were noticed. The synthesis of KP1019 also starts with RuCl3·3H20, which is
dissolved in ethanolic HCl and reacted with an excess of indazole .
Safety information for KP1019
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