KI696 isomer

CAS NO.：1799974-69-8
Empirical Formula: C28H30N4O6S
Molecular Weight: 550.63
Update Date: 2026-05-27 22:45:51

What is KI696 isomer?

Description

KI696 isomer is the less active isomer of KI696. KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction.

References

[1]. Davies TG, et al. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. J Med Chem. 2016 Apr 28;59(8):3991-4006.

Properties of KI696 isomer

Boiling point:	760.5±70.0 °C(Predicted)
Density	1.39±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 125 mg/mL (227.01 mM);Water : < 0.1 mg/mL (insoluble)
pka	4.28±0.10(Predicted)
form	Solid
color	White to off-white

Safety information for KI696 isomer

Computed Descriptors for KI696 isomer

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