KENDOMYCIN
Synonym(s):(−)-TAN 2162
- CAS NO.：183202-73-5
- Empirical Formula: C29H42O6
- Molecular Weight: 486.64
- MDL number: MFCD14635192
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-16 17:44:27
What is KENDOMYCIN?
Description
Kendomycin is a macrolide from Streptomyces which displays potent cytotoxicity against several carcinoma cell lines (GI50 < 100 nM). It also acts as an endothelin receptor antagonist and has antiosteoporotic activities. Certain effects are thought to be mediated through inhibition of proteasomal degradation of proteins.
The Uses of KENDOMYCIN
Kendomycin is a broadly efficacious polyketide macrocycle antibiotic.
The Uses of KENDOMYCIN
Kendomycin is an unusual macrocyclic metabolite containing a rare quinone methide group. Kendomycin is a potent antibacterial agent against Gram positive and Gram negative bacteria, including MRSA strains, also displaying antitumour activity. Kendomycin is a potent endothelin receptor agonist and demonstrates antiosteoporotic activity.
Definition
ChEBI: Kendomycin is a member of benzofurans.
What are the applications of Application
Kendomycin is a broadly efficacious polyketide macrocycle antibiotic
Storage
+4°C
Properties of KENDOMYCIN
| Melting point: | 236-240℃ |
| Boiling point: | 678.5±55.0 °C(Predicted) |
| Density | 1.19±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | Soluble in DMSO |
| form | solid |
| pka | 8.53±0.70(Predicted) |
| color | Yellow |
Safety information for KENDOMYCIN
Computed Descriptors for KENDOMYCIN
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