KAEMPFEROL-3-O-RUTINOSIDE
Synonym(s):3,4′,5,7-Tetrahydroxyflavone 3-rhamnoglucoside;Kaempferol 3-O-β -rutinoside;Nicotiflorin
- CAS NO.：17650-84-9
- Empirical Formula: C27H30O15
- Molecular Weight: 594.52
- MDL number: MFCD03427292
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:19:36
What is KAEMPFEROL-3-O-RUTINOSIDE?
Description
Nicotiflorin is a flavonoid that has been found in I. glandulifera and has antioxidant and neuroprotective activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS radicals with EC50 values of 0.52 and 0.48 mg/ml, respectively, in cell-free assays. Nicotiflorin (1 μM) prevents hydrogen peroxide-induced decreases in tyrosine hydroxylase activity in PC12 cells and cell death in primary rat mesencephalic neurons. It decreases infarct volume by 24.5, 45.8, and 63.2% when administered at doses of 2.5, 5, and 10 mg/kg, respectively, in a rat model of cerebral ischemia-reperfusion injury induced by transient middle central artery occlusion (MCAO).
The Uses of KAEMPFEROL-3-O-RUTINOSIDE
Kaempferol 3-O-β -Rutinoside is a flavonoid antioxidant compound from Cichorium spinosum L. ecotype plants and also may display anti-diabetic activity. It is a component of many plant species including Helianthemum ruficomum.
Definition
ChEBI: Kaempferol-3-rutinoside is a kaempferol O-glucoside that is kaempferol attached to a rutinosyl [6-deoxy-alpha-L-mannosyl-(1->6)-beta-D-glucosyl] residue at position 3 via a glycosidic linkage. It has been isolated from the leaves of Solanum campaniforme. It has a role as a metabolite, a radical scavenger and a plant metabolite. It is a rutinoside, a trihydroxyflavone, a disaccharide derivative and a kaempferol O-glucoside.
General Description
Kaempferol 3-O-β -rutinoside is a bitter tasting flavonol glycoside that was isolated from flowers of a Clematis cultivar.
Properties of KAEMPFEROL-3-O-RUTINOSIDE
| Melting point: | 200°C (dec.) |
| Boiling point: | 941.7±65.0 °C(Predicted) |
| Density | 1.76 |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 6.20±0.40(Predicted) |
| color | Off-White to Yellow |
| Stability: | Hygroscopic |
Safety information for KAEMPFEROL-3-O-RUTINOSIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for KAEMPFEROL-3-O-RUTINOSIDE
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