K-TMZ

CAS NO.：2269482-26-8
Empirical Formula: C7H7N5O2
Molecular Weight: 193.16
Update Date: 2026-01-13 11:18:53

What is K-TMZ?

Description

K-TMZ is a DNA alkylating agent. It increases the concentration of O6-methylated deoxyguanosine in U87 glioblastoma multiforme (GBM) cells in a concentration-dependent manner. K-TMZ reduces cell viability of GBM cell lines lacking or expressing O6-methylguanine DNA methyltransferase (MGMT).

Properties of K-TMZ

Boiling point:	390.5±34.0 °C(Predicted)
Density	1.65±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF:10.0(Max Conc. mg/mL);51.77(Max Conc. mM) DMSO:10.0(Max Conc. mg/mL);51.77(Max Conc. mM) Ethanol:10.0(Max Conc. mg/mL);51.77(Max Conc. mM) Ethanol:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);1.55(Max Conc. mM)
pka	-1.67±0.20(Predicted)

Safety information for K-TMZ

Computed Descriptors for K-TMZ

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