JWH 203 N-pentanoic acid metabolite

CAS NO.：1449675-70-0
Empirical Formula: C21H20ClNO3
Molecular Weight: 369.84
Update Date: 2023-05-04 17:34:33

What is JWH 203 N-pentanoic acid metabolite?

Description

JWH 203 is a synthetic cannabinoid (CB) that displays high affinities for both the central CB₁ receptor (K_i = 8.0 nM) and the peripheral CB₂ receptor (K_i = 7.0 nM).¹ JWH 203 N-pentanoic acid metabolite is an expected metabolite of JWH 203, based on the metabolism of similar compounds.² The physiological and toxicological properties of this compound have not been characterized. This product is intended for forensic and research purposes.

Definition

ChEBI: 1h-indole-1-pentanoic acid, 3-[2-(2-chlorophenyl)acetyl]- is a member of indoles.

References

1. Huffman, J.W., Szklennik, P.V., Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles Bioorg. Med. Chem. Lett. 15(18),4110-4113(2005).
2. Moran, C.L., Le, V.H., Chimalakonda, K.C., et al. Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine Anal. Chem. 83(11),4228-4236(2011).

Properties of JWH 203 N-pentanoic acid metabolite

Boiling point:	592.3±40.0 °C(Predicted)
Density	1.24±0.1 g/cm3(Predicted)
solubility	DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 12.5 mg/ml; Ethanol: 3.3 mg/ml
form	A crystalline solid
pka	4.73±0.10(Predicted)

Safety information for JWH 203 N-pentanoic acid metabolite

Computed Descriptors for JWH 203 N-pentanoic acid metabolite

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