JWH 081-d9

Description

JWH 081-d₉ (exempt preparation) is intended for use as an internal standard for the quantification of JWH 081 by GC- or LC-MS. JWH 081 is categorized as a synthetic cannabinoid.^1,2 It has been found in Spice/K2-type herbal blends and may have neurotoxic properties.³ JWH 081 is regulated as a Schedule I compound in the United States. JWH 081-d₉ (exempt preparation) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

References

1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB₁ and CB₂ receptor binding Drug Alcohol Depend. 60(2),133-140(2000).
2. Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB₁ and CB₂ receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB₂ receptor agonists Bioorg. Med. Chem. 13(1),89-112(2005).
3. Cha, H.J., Seong, Y.H., Song, M.J., et al. Neurotoxicity of synthetic cannabinoids JWH-081 and JWH-210 Biomol. Ther. (Seoul) 23(6),597-603(2015).