JWH 073 N-butanoic acid metabolite

CAS NO.：1307803-52-6
Empirical Formula: C23H19NO3
Molecular Weight: 357.4
MDL number: MFCD18382144
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 00:04:38

What is JWH 073 N-butanoic acid metabolite?

Description

JWH 073 is a mildly selective agonist of the central cannabinoid (CB₁) receptor derived from the aminoalkylindole WIN 55,212-2. The K_i values for binding CB₁ and the peripheral cannabinoid (CB₂) receptor are 8.9 and 38 nM, respectively for a CB₁:CB₂ ratio of 0.23. JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 N-butanoic acid metabolite is expected to be a urinary metabolite of JWH 073, characterized by carboxylation of the N-alkyl chain, based on the metabolism of the closely-related JWH 015 and JWH 018. In urine samples, this metabolite of JWH 018 is almost completely glucuronidated.

The Uses of JWH 073 N-butanoic acid metabolite

JWH-073 (Indole-d7) Butanoic Acid is a by-product in the synthesis of JWH-073 (Indole-d5) Butanoic Acid (J211287). JWH-073 (Indole-d5) Butanoic Acid is labelled JWH-073 Butanoic Acid (J211285), a urinary metabolite of JWH-073 (B693550) which acts as a partial agonist at both the CB1 and CB2 cannabinoid receptors.

Definition

ChEBI: JWH 073 N-butanoic acid metabolite is an indolecarboxamide.

Properties of JWH 073 N-butanoic acid metabolite

Flash point:	9°C
storage temp.	-20°C
solubility	DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml
form	A crystalline solid

Safety information for JWH 073 N-butanoic acid metabolite

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H225:Flammable liquids H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Computed Descriptors for JWH 073 N-butanoic acid metabolite

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