Josamycin

CAS NO.：56689-45-3
Empirical Formula: C42H69NO15
Molecular Weight: 827.99496
Update Date: 2024-03-16 16:28:30

What is Josamycin?

Description

Josamycin was found in the culture broth of Streptomyces narboensis var. josamyceticus by Yamanouchi Pharmaceutical Co. and the Institute of Microbial Chemistry in 1964. It was the first macrolide antibiotic with a 16- membered lactone constituent to be prepared as a single compound. Its lactone structure was first thought to be 17-membered, but later this idea was revised and its identity with leucomycin A3, a component of kitasamycin, was confirmed. Clinically, josamycin is given to children in the form of a base or propionate ester to avoid its bitter taste.

The Uses of Josamycin

Antibacterial.

Definition

ChEBI: Josamycin is a macrolide antibiotic produced by certain strains of Streptomyces narbonensis var. josamyceticus. It has a role as an antibacterial drug and a metabolite. It is a macrolide antibiotic, an aldehyde, a tertiary amino compound, a tertiary alcohol, an acetate ester, a disaccharide derivative and a glycoside.

Safety information for Josamycin

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