JACOZINE

CAS NO.：5532-23-0
Empirical Formula: C18H23NO6
Molecular Weight: 349.38
Update Date: 2023-05-04 17:34:39

What is JACOZINE?

Description

A Senecio alkaloid also present in S. Jacobea, this base has [α] _D - 140° (CHC13) and is hydrolyzed to retronecine and jacozinecic acid. The base contains a methylene group and the ultraviolet spectrum has a single absorption maximum at 233 mμ.

Definition

ChEBI: Jacozine is a pyrrolizine alkaloid that is seneciphylline in which the exocyclic double bond has been converted to the corresponding epoxide. It has a role as a Jacobaea metabolite. It is a macrocyclic lactone, an organic heterotricyclic compound, a pyrrolizine alkaloid, a spiro-epoxide, a tertiary alcohol and a tertiary amino compound. It is functionally related to a seneciphylline.

References

Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor.,Austrai. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Culvenor., ibid, 17,233 (1964)

Properties of JACOZINE

Melting point:

228°C

Safety information for JACOZINE

Computed Descriptors for JACOZINE

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