J104129

CAS NO.：257603-40-0
Empirical Formula: C28H40N2O6
Molecular Weight: 500.64
Update Date: 2026-04-24 14:58:42

What is J104129?

The Uses of J104129

J 104129 Fumarate is a novel muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors.

Biochem/physiol Actions

J104129 is a muscarinic M3 receptor antagonist greater than 100-fold selectivity for M3 over M2 receptors. Its Ki for M3 receptors = 4.2 nM compared to a Ki of 490 nM for M2 receptors. J-104129 showed potent bronchodilator activity in animal studies.

Storage

Store at +4°C

Properties of J104129

storage temp.	2-8°C
solubility	Soluble to 100 mM in DMSO and to 50 mM in ethanol
form	powder
color	white to beige
optical activity	[α]/D -6 to -8°, c = 1 in methanol

Safety information for J104129

Computed Descriptors for J104129

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