Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)-

CAS NO.：104857-29-6
Empirical Formula: C13H10N2O2S
Molecular Weight: 258.3
Update Date: 2026-07-14 16:49:18

What is Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)-?

Description

IC50: 5.71 µM (PCAF/H3_1-21)^[1].

NSC 694621 is a potent PCAF inhibitor, with an IC₅₀ of 5.71 µM (PCAF/H3_1-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells^[1].

NSC 694621 (25 µM; 72 h) exhibits antiproliferative effect to SK-N-SH and HCT116 cells^[1].

Cell Proliferation Assay^[1]

Properties of Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)-

Melting point:	164-166 °C(Solv: methanol (67-56-1))
Boiling point:	470.6±51.0 °C(Predicted)
Density	1.381±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
pka	0.74±0.20(Predicted)
form	Solid
color	White to off-white

Safety information for Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)-

Computed Descriptors for Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)-

New Products

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