ISOSOLAFLORIDINE

Empirical Formula: C27H4SN02
Molecular Weight: 0

What is ISOSOLAFLORIDINE?

Description

Solanum callium yields this alkaloid which forms colourless needles from Et20. It has a specific rotation of [ex] P1 + 44.8° (c 0.85, CHCI3) and the ultraviolet spectrum in EtOH consists of a single absorption maximum at 239 nm. The base has been isolated by hydrolysis of the crude glycoalkaloid present in the above plant. The hydrochloride, m.p. 325-330°C (dec.) with a transition at 31l-2°C, is sparingly soluble in EtOH and has been utilized for the determination of the structure of the alkaloid by X-ray crystallography. The crystals are rectangular plates on the monoclinic system with space group P2 1, a = 6.761, b = 30.563 and c = 6.368 A with Z = 2. Treatment with Ac20 in pyridine furnishes the triacetyl derivative as colourless crystals with m.p. 228-9°C, a specific rotation of [ex]?j + 87.5° (c 1.05, CHCI3) and an ultraviolet spectrum with a single absorption maximum at 236 nm in ethanol.

References

Bird et al., Tetrahedron Lett., 3653 (1976)

Properties of ISOSOLAFLORIDINE

Melting point:

164.5-166.5°C

Safety information for ISOSOLAFLORIDINE

Computed Descriptors for ISOSOLAFLORIDINE

New Products

2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 2,4-Dihydroxybenzaldehyde Dipropyl disulfide Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-Nitrobenzotrifluoride