ISOPILOCARPINE

Empirical Formula: C11H16N2O2
Molecular Weight: 208.26
MDL number: MFCD00272261

What is ISOPILOCARPINE?

Description

The leaves of Pilocarpus pennatifolius Lem. and P. jaborandi Holmes contain this alkaloid which is a colourless oily liquid. A number of salts and derivatives have been prepared, e.g. the hydrochloride hemihydrate, m.p. 127°C or 159°C (dry); hydrobromide, m.p. 147°C; nitrate, m.p. 159°C; aurichloride, m.p. 158-9°C; platinichloride, m.p. 226-7°C; picrate, m.p. 161°C and the methiodide, m.p. 114°C.

References

Jowett.,J. Chern. Soc., 77, 483 (1900) Jowett., ibid, 87, 794 (1905) Burtles, Pyman, Roylance., ibid, 581 (1925) Preobrashenski, Wompe, Preobrashenski., Ber., 66, 1187 (1933) Poljakova et al., ibid, 69, 1314 (1936) DeY.,J. Chern. Soc., 1057 (1937) Preobrashenski., Chern. Abstr., 47,4345 (1953)

Properties of ISOPILOCARPINE

Boiling point:	261 °C/IO mm
pka	pKa 7.18(H2O,t =15) (Uncertain)

Safety information for ISOPILOCARPINE

Computed Descriptors for ISOPILOCARPINE

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