Isoniazid-D4
- CAS NO.：774596-24-6
- Empirical Formula: C6H7N3O
- Molecular Weight: 137.14
- MDL number: MFCD09840815
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-29 17:52:28
What is Isoniazid-D4?
Chemical properties
Crystalline Solid
The Uses of Isoniazid-D4
Labelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).
What are the applications of Application
Isoniazid-d4 is an inhibitor and an inducer of various isoforms of CYP450
Properties of Isoniazid-D4
| Melting point: | 171.40C |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Pale Beige |
Safety information for Isoniazid-D4
Computed Descriptors for Isoniazid-D4
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