ISOBORNYL THIOCYANOACETATE

Chemical properties

Yellow oily liquid; terpene-like odor. Very soluble in alcohol, benzene, chloroform, and ether; practically insoluble in water. Combustible.

Originator

Bornate,Wyeth,US,1946

The Uses of ISOBORNYL THIOCYANOACETATE

Insecticide, especially in cattle sprays.

Definition

The technical grade contains 82% or more of isobornyl thiocyanoacetate, also other terpenes and derivatives.

Manufacturing Process

200 g of camphene and 150 g of chloroacetic acid were heated 16 hours at 125°C, cooled to room temperature and the resulting product washed with water. In this way, 177 g of isobornyl monochloroacetate, analyzing 12.8%, by weight, chlorine was recovered. 174 g of the isobornyl monochloroacetate was dissolved in 300 cc of ethyl alcohol, 100 g of potassium thiocyanate added to this solution and the mixture refluxed for a period of 8 hours. 276 g of a product was recovered, which analyzed as follows: chlorine, 0.2% by wt. and sulfur, 10.9% by wt. This analysis shows the product to be principally isobornyl thiocyanoacetate.

Therapeutic Function

Pediculicide

Hazard

Toxic by ingestion, strong irritant.