Irinotecan hydrochloride trihydrate
- CAS NO.：136572-09-3
- Molecular Weight: 0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-29 15:43:00
What is Irinotecan hydrochloride trihydrate?
Definition
ChEBI: Irinotecan hydrochloride hydrate is a hydrate that is the trihydrate form of irinotecan hydrochloride. Onivyde is used in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active. It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an antineoplastic agent, an apoptosis inducer and a prodrug. It contains an irinotecan hydrochloride (anhydrous).
Properties of Irinotecan hydrochloride trihydrate
| Melting point: | 256.5 °C |
Safety information for Irinotecan hydrochloride trihydrate
Computed Descriptors for Irinotecan hydrochloride trihydrate
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