INNO206

CAS NO.：1361644-26-9
Empirical Formula: C37H42N4O13
Molecular Weight: 750.75
SAFETY DATA SHEET (SDS)
Update Date: 2026-07-16 07:06:08

What is INNO206?

Biological Activity

Aldoxorubicin (INNO-206) is an albumin-bound prodrug of doxorubicin, a DNA topoisomerase II inhibitor, released from albumin under acidic conditions. It has potent antitumor activity in various cancer cell lines and mouse tumor models.

in vitro

Aldoxorubicin (INNO-206) (0.27 to 2.16 μM) inhibits blood vessel formation and reduces multiple myeloma cell growth in a pH-dependent fashion.

in vivo

Aldoxorubicin (INNO-206) (10.8 mg/kg, i.v.) shows significantly smaller tumor volumes and IgG levels on days 28, and is well tolerated with 90% of mice surviving until the termination of the study in the mice bearing the LAGκ-1A tumor.

Properties of INNO206

Density	1.60±0.1 g/cm3(Predicted)
storage temp.	-80°, stored under nitrogen,unstable in solution, ready to use.
solubility	DMSO : 75 mg/mL (99.90 mM)
form	Solid
pka	7.36±0.60(Predicted)
color	Purple to purplish red

Safety information for INNO206

Computed Descriptors for INNO206

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