SuO-Glu-Val-Cit-PAB-MMAE

CAS NO.：1895916-24-1
Empirical Formula: C67H103N11O17
Molecular Weight: 1334.6
Update Date: 2026-03-18 11:52:23

What is SuO-Glu-Val-Cit-PAB-MMAE?

Biological Activity

SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Properties of SuO-Glu-Val-Cit-PAB-MMAE

Density	1.26±0.1 g/cm3(Predicted)
pka	13.29±0.70(Predicted)
form	Solid
color	White to off-white

Safety information for SuO-Glu-Val-Cit-PAB-MMAE

Computed Descriptors for SuO-Glu-Val-Cit-PAB-MMAE

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