14-Oxa-17,18-dithia-4,7,10-triazatriacontanoic acid, 4,10-bis[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-7-methyl-13-oxo-, 2-(dodecyldithio)ethyl ester

CAS NO.：2566523-07-5
Empirical Formula: C73H143N3O8S8
Molecular Weight: 1447.46
Update Date: 2026-05-28 03:30:06

What is 14-Oxa-17,18-dithia-4,7,10-triazatriacontanoic acid, 4,10-bis[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-7-methyl-13-oxo-, 2-(dodecyldithio)ethyl ester?

Description

113-O16B is a disulfide bond-containing ionizable cationic lipidoid.¹ It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA.

References

1. Chen, J., Ye, Z., Huang, C., et al. Lipid nanoparticle-mediated lymph node-targeting delivery of mRNA cancer vaccine elicits robust CD8⁺ T cell response Proc. Natl. Acad. Sci. USA 119(34),e2207841119(2022).

Properties of 14-Oxa-17,18-dithia-4,7,10-triazatriacontanoic acid, 4,10-bis[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-7-methyl-13-oxo-, 2-(dodecyldithio)ethyl ester

Boiling point:	1131.8±65.0 °C(Predicted)
Density	1.048±0.06 g/cm3(Predicted)
solubility	Ethanol: Soluble
pka	7.73±0.50(Predicted)

Safety information for 14-Oxa-17,18-dithia-4,7,10-triazatriacontanoic acid, 4,10-bis[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-7-methyl-13-oxo-, 2-(dodecyldithio)ethyl ester

Computed Descriptors for 14-Oxa-17,18-dithia-4,7,10-triazatriacontanoic acid, 4,10-bis[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-7-methyl-13-oxo-, 2-(dodecyldithio)ethyl ester

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