Propanamide, N-(phenyl-2,3,4,5,6-d5)-N-[1-(2-phenylethyl)-4-piperidinyl]-, hydrochloride (1:1)

Description

Fentanyl-d₅ (hydrochloride) (CRM) is a certified reference material intended for use as an internal standard for the quantification of fentanyl by GC- or LC-MS. Fentanyl is categorized as an opioid.^1,2 It is more effective than morphine at reducing pain but is also more lethal.³ Fentanyl is highly abused and is associated with many fatal overdoses.⁴ Fentanyl is regulated as a Schedule II compound in the United States. Fentanyl-d₅ (hydrochloride) (CRM) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

References

1. Burns, S.M., Cunningham, C.W., and Mercer, S.L. DARK classics in chemical neuroscience: Fentanyl ACS Chem. Neurosci. 9(10),2428-2437(2018).
2. Raynor, K., Kong, H., Chen, Y., et al. Pharmacological characterization of the cloned κ-, δ-, and μ-opioid receptors Mol. Pharm. 45(2),330-334(1994).
3. Higashikawa, Y., and Suzuki, S. Studies on 1-(2-phenethyl)-4-(N-propionylanilino)piperidine (fentanyl) and its related compounds. VI. Structure-analgesic activity relationship for fentanyl, methyl-substituted fentanyls and other analogues Forensic Toxicol. 26(1),1-5(2008).
4. Armenian, P., Vo, K.T., Barr-Walker, J., et al. Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review Neuropharmacology 134(Pt A),121-132(2018).