Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
- CAS NO.：2512228-06-5
- Empirical Formula: C12H15NO6
- Molecular Weight: 269.25
- MDL number: MFCD29041934
- Update Date: 2026-02-03 20:41:04
![Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester Structural](https://img.chemicalbook.in/CAS/20211123/GIF/2512228-06-5.gif)
What is Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester?
Biological Activity
Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.
Properties of Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
| Boiling point: | 389.8±50.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3(Predicted) |
| form | Solid |
| color | White to off-white |
Safety information for Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
Computed Descriptors for Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 2,4-Dihydroxybenzaldehyde Dipropyl disulfide Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
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