(S)-dibutyl(3-hydroxybutyl)phosphate

CAS NO.：2108602-99-7
Empirical Formula: C12H27O5P
Molecular Weight: 282.31
Update Date: 2026-05-28 01:29:59

What is (S)-dibutyl(3-hydroxybutyl)phosphate?

Description

Dibutyl 3-hydroxybutyl phosphate (TBP-OH; ) is a compound produced from the metabolism of the organophosphorus solvent, tributyl phosphate (TBP). Incubation of goldfish liver microsomes in the presence of NADPH has been shown to convert TBP into TBP-OH and dibutyl phosphate.¹ TBP-OH has also been produced during radiolysis of TBP.² (S)-TBP-OH is an optically active isomer of TBP-OH.

References

1. Sasaki, K., Suzuki, T., Takeda, M., et al. Metabolism of phosphoric acid triesters by goldfish, Carassius auratus Eisei Kagaku 31(6),397-404(1985).
2. Lesage, D., Virelizier, H., Jankowski, C.K., et al. Identification of minor products obtained during radiolysis of tributylphosphate (TBP) Spectroscopy 13(4),275-290(1997).

Properties of (S)-dibutyl(3-hydroxybutyl)phosphate

Boiling point:	368.1±25.0 °C(Predicted)
Density	1.054±0.06 g/cm3(Predicted)
solubility	DMF: 25 mg/ml; DMSO: 15 mg/ml; Ethanol: 15 mg/ml; PBS (pH 7.2): 1 mg/ml
pka	14.73±0.20(Predicted)

Safety information for (S)-dibutyl(3-hydroxybutyl)phosphate

Computed Descriptors for (S)-dibutyl(3-hydroxybutyl)phosphate

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