Idazoxan
- CAS NO.：79944-58-4
- Empirical Formula: C11H12N2O2
- Molecular Weight: 204.23
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-21 16:56:50
What is Idazoxan?
The Uses of Idazoxan
alpha2-adrenergic blocker
Definition
ChEBI: A benzodioxine that is 2,3-dihydro-1,4-benzodioxine in which one of the hydrogens at position 2 has been replaced by a 4,5-dihydro-1H-imidazol-2-yl group.
Metabolic pathway
When rats are administered radio-labeled idazoxan orally, the biotransformation of idazoxan is by hydroxylation at the 6- and 7-positions to form phenolic metabolites, which are excreted as glucuronide and sulfate metabolites in the urine, but unconjugated in the feces. Other minor metabolic pathways are 5-hydroxylation or oxidative degradation of the imidazoline ring, but these pathways are of quantitatively minor importance in rats.
Properties of Idazoxan
| Boiling point: | 155-165 °C(Press: 0.1 Torr) |
| Density | 1.39±0.1 g/cm3(Predicted) |
| pka | 9.51±0.40(Predicted) |
Safety information for Idazoxan
Computed Descriptors for Idazoxan
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