ICI 204,448 HYDROCHLORIDE
Synonym(s):(±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride;R,S-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl] phenoxy]-acetic acid hydrochloride
- CAS NO.：121264-04-8
- Empirical Formula: C23H27Cl3N2O4
- Molecular Weight: 501.83
- MDL number: MFCD00153814
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-14 09:55:04
What is ICI 204,448 HYDROCHLORIDE?
The Uses of ICI 204,448 HYDROCHLORIDE
Opioid agonists exert a broad range of effects on the immune system ranging from inflammatory response modulation to opioid and chemokine receptor expression. ICI 204448 is a kappa-opioid receptor with antinociceptive properties.
What are the applications of Application
ICI-204,448 hydrochloride is a peripherally acting KOR (κ-opioid receptor) agonist.
Biological Activity
Peripherally acting κ agonist.
Storage
Store at RT
Properties of ICI 204,448 HYDROCHLORIDE
| storage temp. | Store at RT |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 12 mg/mL |
| form | solid |
| color | white |
Safety information for ICI 204,448 HYDROCHLORIDE
Computed Descriptors for ICI 204,448 HYDROCHLORIDE
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