I-OME-AG 538
Synonym(s):α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3′,4′-dihydroxyphenyl)ketone;I-OMe-AG 538
- CAS NO.：1094048-77-7
- Empirical Formula: C17H12INO5
- Molecular Weight: 437.19
- MDL number: MFCD03453582
- Update Date: 2026-07-14 16:49:18
What is I-OME-AG 538?
The Uses of I-OME-AG 538
I-OMe-Tyrphostin AG 538 has been used as a cell signaling inhibitor in PC-1 cell lines. It has also been used in high throughput screening assays for IGF1R inhibitors.
Definition
ChEBI: 2-[(3,4-dihydroxyphenyl)-oxomethyl]-3-(4-hydroxy-3-iodo-5-methoxyphenyl)-2-propenenitrile is a member of chalcones.
Biochem/physiol Actions
Insulin growth factor 1 (IGF-1) receptor protein tyrosine kinase inhibitor.
Properties of I-OME-AG 538
| storage temp. | -20°C |
| solubility | DMSO : 50 mg/mL (114.37 mM; Need ultrasonic) |
| form | solid |
| color | Yellow to orange |
Safety information for I-OME-AG 538
Computed Descriptors for I-OME-AG 538
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