Hydrocortisone aceponate
- CAS NO.:74050-20-7
- Empirical Formula: C26H36O7
- Molecular Weight: 460.56
- MDL number: MFCD00866010
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is Hydrocortisone aceponate?
Description
Hydrocortisone aceponate is the 17-a-propionate derivative of hydrocortisone-21-acetate. Its is reportedly significantly superior to the latter in the treatment of dermatoses of varying severity.
Chemical properties
White to Off-White Solid
Originator
Beiersdorf (W.Germany)
The Uses of Hydrocortisone aceponate
A new topical hydrocortisone derivative with esterification in positions 17 and 21, inhibit the incorporation of [3H]thymidine in DNA in human skin fibroblasts less strongly than the halogenated glucocorticosteroids betamethasone 17-valerate and clobetasol 17-propionate. Glucocorticosteroid
The Uses of Hydrocortisone aceponate
A new topical hydrocortisone derivative with esterification in positions 17 and 21, inhibit the incorporation of [3H]thymidine in DNA in human skin fibroblasts less strongly than the halogenated glucocorticosteroids betamethasone 17-valerate and clobetasol 17-propionate. Glucocorticosteroid.
Definition
ChEBI: Hydrocortisone aceponate is a corticosteroid hormone.
brand name
Retef
Properties of Hydrocortisone aceponate
| Melting point: | 144-146°C |
| Density | 1.23±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Pale Beige |
Safety information for Hydrocortisone aceponate
Computed Descriptors for Hydrocortisone aceponate
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