HUMAN IGF-II
Synonym(s):IGF-II
- CAS NO.：96081-16-2
- Empirical Formula: C24H36N4O9
- Molecular Weight: 0
- MDL number: MFCD00241895
- Update Date: 2025-01-27 09:38:02
What is HUMAN IGF-II?
Biochem/physiol Actions
Insulin-like growth factor II (IGF-II) also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. Expression of IGF-II is highest in fetal tissues, where it is believed to play a major role in overall growth and development. After birth IGF-II expression decreases to much lower levels in a variety of tissues. IGF-II is produced also in several tumors. IGF-II binds to IGF-II receptor (IGF-IIR), to IGF-IR and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-IR. However, during embryogenesis the roles of both IGF-IIR and IR may be significant in promoting normal growth.
Properties of HUMAN IGF-II
| storage temp. | -20°C |
| form | lyophilized powder |
Safety information for HUMAN IGF-II
Computed Descriptors for HUMAN IGF-II
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