HS-PEG5-OH
- CAS NO.：248582-03-8
- Empirical Formula: C10H22O5S
- Molecular Weight: 254.34
- MDL number: MFCD31558252
- Update Date: 2026-02-03 20:41:04
What is HS-PEG5-OH?
Biological Activity
Thiol-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of HS-PEG5-OH
| Boiling point: | 363.2±37.0 °C(Predicted) |
| Density | 1.102±0.06 g/cm3(Predicted) |
| pka | 9?+-.0.10(Predicted) |
Safety information for HS-PEG5-OH
Computed Descriptors for HS-PEG5-OH
New Products
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