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HomeProduct name listHS-PEG11-CH2CH2N3

HS-PEG11-CH2CH2N3

  • CAS NO.:2148986-08-5
  • Empirical Formula: C24H49N3O11S
  • Molecular Weight: 587.73
  • MDL number: MFCD34470046
  • Update Date: 2025-04-17 18:22:24
HS-PEG11-CH2CH2N3 Structural

What is HS-PEG11-CH2CH2N3?

Biological Activity

HS-PEG11-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Safety information for HS-PEG11-CH2CH2N3

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