Homatropine Hydrobromide
Synonym(s):DL -endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide;DL -Homatropine hydrobromide;Tropine mandelate hydrobromide
- CAS NO.：51-56-9
- Empirical Formula: C16H22BrNO3
- Molecular Weight: 356.25
- MDL number: MFCD00012676
- EINECS: 200-105-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:03:02
What is Homatropine Hydrobromide?
Description
Homatropine is an anticholinergic agent. It reduces acetylcholine-induced contractions of isolated goat detrusor muscle strips when used at a concentration of 5 μM. Homatropine (1 μM) inhibits acetylcholine- or methacholine-induced contraction of isolated rat anococcygeus muscle. It inhibits serotonin- or thrombin-induced platelet aggregation in isolated sheep platelet-rich plasma (IC50s = 4.3 and 100 μM, respectively). Topical ophthalmic administration of homatropine induces partial mydriasis in Angora goats.
The Uses of Homatropine Hydrobromide
Homatropine is an anticholinergic agent. Homatropine acts as an inhibitor of the muscarinic acetylcholine receptors. Homatropine is used in eye drops as a cycloplegic and as a mydriatic, to dilate the pupil.
Properties of Homatropine Hydrobromide
| Melting point: | 214-217 °C |
| storage temp. | 2-8°C |
| solubility | Freely soluble in water, sparingly soluble in alcohol. |
| form | neat |
| color | White to Off-White |
| Water Solubility | soluble |
Safety information for Homatropine Hydrobromide
Computed Descriptors for Homatropine Hydrobromide
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