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hodgkinsine

hodgkinsine Structural

What is hodgkinsine?

Definition

ChEBI: Hodgkinsine is a pyrroloindole.

Biological Activity

Hodgkinsine is a pyrrolidinoindoline alkaloid that has been found in P. colorata and has analgesic activity.1 It increases latency to paw licking in the hot plate test and latency to tail withdrawal in the tail-flick test in mice when administered at a dose of 5 mg/kg.

References

1.Amador, T.A., Verotta, L., Nunes, D.S., et al.Antinociceptive profile of hodgkinsinePlanta Med.66(8)770-772(2000)

Properties of hodgkinsine

Density  1.258±0.06 g/cm3(Predicted)
storage temp.  -20°C
form  A solid
pka 8.17±0.40(Predicted)

Safety information for hodgkinsine

Computed Descriptors for hodgkinsine

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