Hh-Ag 1.3
Synonym(s):Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem
- CAS NO.：364590-63-6
- Empirical Formula: C28H28ClN3OS
- Molecular Weight: 490.06
- MDL number: MFCD14636155
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:01
What is Hh-Ag 1.3?
The Uses of Hh-Ag 1.3
Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.
What are the applications of Application
Smoothened Agonist, HCl is a Hh pathway agonist that interacts with the heptahelical domain of Smo
Properties of Hh-Ag 1.3
| Boiling point: | 688.6±55.0 °C(Predicted) |
| Density | 1.30±0.1 g/cm3(Predicted) |
| pka | 10?+-.0.40(Predicted) |
| form | White to off-white solid. |
| Water Solubility | Soluble in water. |
| Sensitive | Light Sensitive & Hygroscopic |
Safety information for Hh-Ag 1.3
Computed Descriptors for Hh-Ag 1.3
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