HEXADIMETHRINE BROMIDE
Synonym(s):1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide;Hexadimethrine bromide;Polybrene
- CAS NO.:28728-55-4
- Empirical Formula: C39H90Br6N6X2
- Molecular Weight: 1122.6
- MDL number: MFCD00133397
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-11-19 11:01:56
What is HEXADIMETHRINE BROMIDE?
The Uses of HEXADIMETHRINE BROMIDE
Hexadimethrine bromide can be used to transfect mammalian cells with DNA. It can be used to increase the efficiency of lipofection transfections.
Hexadimethrine bromide has been used for lentivirus infection in cells. It has been used for infection of cells with retroviral supernatant.
The Uses of HEXADIMETHRINE BROMIDE
Antiheparin agent. A 3mg quantity has been found to enhance peptide degradation in automated sequential analysis.
The Uses of HEXADIMETHRINE BROMIDE
Used as a protein/peptide carrier for protein sequencing.
What are the applications of Application
Hexadimethrine bromide is useful as a peptide carrier during protein sequencing
What are the applications of Application
Polybrene? is a highly efficient infection reagent used to introduce retroviral vectors into mammalian cells
Definition
ChEBI: Hexadimethrine bromide is a polymer.
General Description
Hexadimethrine bromide is a quaternary ammonium compound which works as a heparin antagonist. It is also involved in the transformation of low molecular weight DNA.
Storage
Store at +4°C
Purification Methods
Purify it by chromatography on Dowex 50 and/or by filtration through alumina before use [Frank Hoppe-Seyler's Z Physiol Chemie 360 997 1979]. It is hygroscopic, and its solubility in H2O is 10%.
Properties of HEXADIMETHRINE BROMIDE
| storage temp. | 2-8°C |
| solubility | H2O: 0.1 g/mL, clear to slightly hazy, colorless to faintly yellow |
| form | gelatinous solid |
| color | White to off-white |
| Water Solubility | 10mg/ml in Water |
| Merck | 13,4702 |
| CAS DataBase Reference | 28728-55-4 |
Safety information for HEXADIMETHRINE BROMIDE
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for HEXADIMETHRINE BROMIDE
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