Herkinorin

CAS NO.：862073-77-6
Empirical Formula: C28H30O8
Molecular Weight: 494.53
MDL number: MFCD10574986
EINECS: 202-713-4
Update Date: 2026-05-11 16:31:51

What is Herkinorin?

Description

Herkinorin (Item No. 20925) is an analytical reference standard that is functionally categorized as an opioid. It is a natural neoclerodane diterpene from S. divinorum that preferentially activates the μ-opioid receptor. Unlike the peptide DAMGO , herkinorin activates μ-opioid receptors without inducing arrestin-mediated receptor internalization. Herkinorin has antinociceptive effects in rats. It has been identified as a novel psychoactive substance in multiple agitated emergency department patients screened in a non-targeted manner. This product is intended for research and forensic applications.

The Uses of Herkinorin

Herkinorin is an opioid analgesic and an analogue of Salvinorin A (S100900). Salvinorin A is a potent and selective kappa-opioid receptor agonist.

Properties of Herkinorin

Melting point:	165-170 °C
Boiling point:	635.6±55.0 °C(Predicted)
Density	1.30±0.1 g/cm3(Predicted)
solubility	Acetonitrile: 1 mg/ml; DMF: 1 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 2 mg/ml
form	A crystalline solid

Safety information for Herkinorin

Computed Descriptors for Herkinorin

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