HEPTAMETHYLDISILAZANE
- CAS NO.：134340-00-4
- Empirical Formula: C7H21NSi2
- Molecular Weight: 175.42
- MDL number: MFCD00008262
- EINECS: 678-035-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-16 09:55:37
What is HEPTAMETHYLDISILAZANE?
Physical properties
colorless liquid, bp 70°Cat 25 mm Hg; its hydrochloride salt, mp 191 °C.
The Uses of HEPTAMETHYLDISILAZANE
Methanamine, 1,1-Bis(trimethylsilyl) is reagent used for the preparation of N-bis(trimethylsilyl)methyl amines, imines, as a synthetic equivalent of N-methyl, N- (trimethylsilyl)methyl carbanion, and [N-CH] dianion synthons, as an N-protecting group.
Preparation
It is prepared by lithium metal mediated reductive silylation of trimethylsilyl cyanide.
Properties of HEPTAMETHYLDISILAZANE
| Boiling point: | 144-147 °C(lit.) |
| Density | 0.799 g/mL at 20 °C(lit.) |
| refractive index | n |
| solubility | sol ether, alcohol, dichloromethane, and most organic
solvents; hydrochloride salt sol in H2O, alcohol, DMF, DMSO. |
| pka | 11.57±0.29(Predicted) |
| form | clear liquid |
| color | Colorless to Almost colorless |
Safety information for HEPTAMETHYLDISILAZANE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H226:Flammable liquids H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for HEPTAMETHYLDISILAZANE
New Products
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![3-[BIS(TRIMETHYLSILYL)AMINO]PHENYLMAGNESIUM CHLORIDE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB2221838.gif)
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