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HomeProduct name listHaplophytine

Haplophytine

Haplophytine Structural

What is Haplophytine?

Description

Yates and his colleagues have recently revised the structure of this alkaloid which is the major constituent of Haplophyton cirnicidurn.

Description

Haplophytine is an insecticidal alkaloid that has been used since Aztec times. It was?first isolated?from the Mexican plant?Haplophyton cimicidum?by H. R. Snyder and co-workers in 1951. Its structure was?determined?by a research team led by P. Yates in 1967; but its total synthesis (in 29 steps!) wasn’t achieved until T. Fukuyama, H. Tokuyama, and colleagues?reported?it this year.

Definition

ChEBI: Haplophytine is a member of carbazoles.

References

Yates et al.,J. Arner. Chern. Soc., 95, 7842 (1973)

Properties of Haplophytine

Melting point: 290-293° (rapid heating, starting at 250°); mp 300-302° (Yates et al., loc. cit.)
alpha  D25 +109.0° (chloroform)

Safety information for Haplophytine

Computed Descriptors for Haplophytine

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