H3B-616
- CAS NO.：2468199-06-4
- Empirical Formula: C23H24FN3O3
- Molecular Weight: 409.46
- Update Date: 2023-03-31 09:12:57
What is H3B-616?
Description
H3B-616 is potent allosteric inhibitor of CPS1 (IC50 = 66 nM). Carbamoyl phosphate synthetase 1 (CPS1) is a potential synthetic lethal target in LKB1-deficient nonsmall cell lung cancer, where its overexpression supports the production of pyrimidine synthesis.
Safety information for H3B-616
New Products
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