H2N-PEG4-tBu
Synonym(s):tert-Butyl 1-amino-3,6,9,12-tetraoxapentadecan-15-oate;H2N-dPEG(4)-CO-OtBu;H2N-PEG4-CH2CH2COOtBu
- CAS NO.：581065-95-4
- Empirical Formula: C15H31NO6
- Molecular Weight: 321.41
- MDL number: MFCD11041116
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:24
What is H2N-PEG4-tBu?
Description
Amino-PEG4-t-butyl ester is a PEG reagent containing an amino (NH2) and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl (Boc) can be deprotected under acidic conditions.
The Uses of H2N-PEG4-tBu
is a linker-cytotoxin conjugate. Linker-cytotoxin conjugate is related to antibody-cytotoxin and antibody-drug conjugates and related compounds.
Properties of H2N-PEG4-tBu
| Boiling point: | 400.1±35.0 °C(Predicted) |
| Density | 1.040±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 8.74±0.10(Predicted) |
| form | clear liquid |
| color | Colorless to Light yellow |
| CAS DataBase Reference | 581065-95-4 |
Safety information for H2N-PEG4-tBu
Computed Descriptors for H2N-PEG4-tBu
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