PACAP 1-27
Synonym(s):PACAP 27 Amide, Ovine - CAS 127317-03-7 - Calbiochem;PACAP-27;Pituitary Adenylate Cyclase Activating Polypeptide, HSDGIFTDSYSRYRKQMAVKKYLAAVL-NH₂
- CAS NO.:127317-03-7
- Empirical Formula: C142H224N40O39S
- Molecular Weight: 3147.61
- MDL number: MFCD00167418
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-23 17:25:30
What is PACAP 1-27?
The Uses of PACAP 1-27
Pituitary Adenylate Cyclase-Activating Polypeptide 1-27 (PACAP 1-27) is a neuropeptide that stimulates adenylyl cyclase.
Biological Functions
PACAP 1-27 is an endogenous neuropeptide and is the C-terminally truncated form of PACAP 38. PACAP 27 has considerable homology with vasoactive intestinal peptide (VIP) but is >100 fold more potent than VIP as an agonist of the PAC1 receptor. PACAP 27 functions in the control of anterior pituitary hormone secretion, vasodilation, adrenaline secretion, insulin secretion and immunosuppression.
Biological Activity
PACAP 1-27, also known as PACAP 27 Amide, is an endogenous neuropeptide showing considerable homology with vasoactive intestinal peptide (VIP). Potently stimulates adenylyl cyclase.
Storage
Store at -20°C
Properties of PACAP 1-27
| Density | 1.45±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2OPeptide Solubility and Storage Guidelines:1.??Calculate the length of the peptide.2.??Calculate the overall charge of the entire peptide according to the following table:3.??Recommended solution: |
| form | solid |
| color | white |
| Water Solubility | Soluble to 1 mg/ml in water |
Safety information for PACAP 1-27
Computed Descriptors for PACAP 1-27
| InChIKey | RZGBUJXSKLDAFE-XVTUQGJWNA-N |
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