H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
- CAS NO.:121204-87-3
- Empirical Formula: C109H163N25O32S
- Molecular Weight: 2367.67
- MDL number: MFCD00143562
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:12:40
What is H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH?
The Uses of H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
[Ala1,3,11,15]-Endothelin 1 may be used to assess the effects of endothelin-1 and [Ala1,3,11,15]-endothelin 1 produced by ETA and ETB receptors, in the presence of BQ-123, in anaesthetized rat.
General Description
[Ala1,3,11,15]-Endothelin 1 is a linear endothelin (ET)-1 analogue, and acts as an ETB receptor agonist. ET-1 is a peptide that acts as both, a vasodilator and a vasoconstrictor. It is a ligand for ET receptor, which is of two types, ETA and ETB. ETB receptor is found in the vascular endothelial cells of cardiovascular tissues.
Biochem/physiol Actions
Selective agonist for ETB endothelin receptors.
Properties of H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
| Boiling point: | 2391.5±65.0 °C(Predicted) |
| Density | 1.319±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| form | Solid |
| Water Solubility | Soluble to 1 mg/ml in water |
Safety information for H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
| Signal word | Danger |
| Pictogram(s) |
![]() Skull and Crossbones Acute Toxicity GHS06 |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P284:Wear respiratory protection. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
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![([125I]-TYR)-ENDOTHELIN-1 (HUMAN, BOVINE, DOG, MOUSE, PORCINE, RAT)](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB1484474.gif)



![ENDOTHELIN-1 [ALA1,3,11,15] [3-(125I)TYR] (HUMAN)](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB4439804.gif)

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