H-8 DIHYDROCHLORIDE
Synonym(s):H-8, Dihydrochloride;N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide hydrochloride;N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide, 2HCl, PKA Inhibitor I
- CAS NO.：113276-94-1
- Empirical Formula: C12H17Cl2N3O2S
- Molecular Weight: 338.25
- MDL number: MFCD00036962
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:17:51
What is H-8 DIHYDROCHLORIDE?
Description
The H series isoquinolinesulfonamide protein kinase (PK) inhibitors are widely used to block signaling pathways to elucidate mechanisms of cellular regulation and signal transduction. H-
Chemical properties
white to off-white crystalline solid
The Uses of H-8 DIHYDROCHLORIDE
Active inhibitor of cyclic-nucleotide-dependent protein kinases.
What are the applications of Application
H-8 ? 2HCl is a selective inhibitor of PKA and cGKI
Biochem/physiol Actions
cAMP and cGMP-dependent protein kinase inhibitor.
Properties of H-8 DIHYDROCHLORIDE
| Melting point: | 221-222℃ (methanol water ) |
| storage temp. | 2-8°C |
| solubility | ethanol: 25 mg/mL, clear, colorless |
| form | Lyophilized |
| color | White to Off-White |
| CAS DataBase Reference | 113276-94-1(CAS DataBase Reference) |
Safety information for H-8 DIHYDROCHLORIDE
Computed Descriptors for H-8 DIHYDROCHLORIDE
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![(S)-(+)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLYNYL)SULFONYL]HOMOPIPERAZINE](https://img.chemicalbook.in/CAS/GIF/451462-58-1.gif)
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