GYKI 52466 dihydrochloride
- CAS NO.：2319722-40-0
- Empirical Formula: C17H16ClN3O2
- Molecular Weight: 329.78
- MDL number: MFCD03453303
- Update Date: 2026-05-11 19:39:08
What is GYKI 52466 dihydrochloride?
Biological Activity
GYKI 52466 dihydrochloride is a selective noncompetitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >50 μM for AMPA-, kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant. Has anti-proliferative effects in transformed cells.
Storage
Store at -20°C
Properties of GYKI 52466 dihydrochloride
| solubility | Soluble to 50 mM in DMSO and to 10 mM in water |
| form | Solid |
| color | Yellow to orange |
Safety information for GYKI 52466 dihydrochloride
Computed Descriptors for GYKI 52466 dihydrochloride
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