GW 766994

CAS NO.：408303-43-5
Empirical Formula: C21H24Cl2N4O3
Molecular Weight: 451.35
MDL number: MFCD31656783
Update Date: 2026-04-22 18:57:36

What is GW 766994?

Description

GW 766994 is an antagonist of chemokine (C-C motif) receptor 3 (CCR3) with a K_i value of 13.8 nM in an assay of eosinophil chemotaxis induced by chemokine (C-C motif) ligand 11 (CCL11). It decreases CCL11-induced cyclin-dependent kinase 5 (Cdk5) and tau phosphorylation and production of amyloid β (1-42) (Aβ42) in isolated mouse hippocampal neurons when used at a concentration of 10 μM.

Properties of GW 766994

Boiling point:	685.8±55.0 °C(Predicted)
Density	1.331±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:56.0(Max Conc. mg/mL);124.07(Max Conc. mM)
form	A solid
pka	13.40±0.46(Predicted)
color	Light yellow to yellow

Safety information for GW 766994

Computed Descriptors for GW 766994

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