GW 766994
- CAS NO.：408303-43-5
- Empirical Formula: C21H24Cl2N4O3
- Molecular Weight: 451.35
- MDL number: MFCD31656783
- Update Date: 2026-07-27 17:00:41
What is GW 766994?
Description
GW 766994 is an antagonist of chemokine (C-C motif) receptor 3 (CCR3) with a Ki value of 13.8 nM in an assay of eosinophil chemotaxis induced by chemokine (C-C motif) ligand 11 (CCL11). It decreases CCL11-induced cyclin-dependent kinase 5 (Cdk5) and tau phosphorylation and production of amyloid β (1-42) (Aβ42) in isolated mouse hippocampal neurons when used at a concentration of 10 μM.
Properties of GW 766994
| Boiling point: | 685.8±55.0 °C(Predicted) |
| Density | 1.331±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO:56.0(Max Conc. mg/mL);124.07(Max Conc. mM) |
| form | A solid |
| pka | 13.40±0.46(Predicted) |
| color | Light yellow to yellow |
Safety information for GW 766994
Computed Descriptors for GW 766994
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