GSK990
- CAS NO.：1816331-64-2
- Empirical Formula: C23H23N7O2
- Molecular Weight: 429.48
- Update Date: 2026-01-05 11:31:08
What is GSK990?
Description
GSK990 is a structurally similar compound which is inactive as an IDH1 inhibitor. GSK990 may be used as a native control to GSK864. SK864 has been shown to be selective in vitro for IDH1 over other classes of proteins (7TMs, ion channels, kinases) and chemoproteomic studies with GSK321, an analog of GSK864, confirm selective binding of IDH1 by this chemical series. GSK864 has a pharmacokinetic profile suitable for in vivo studies. (http://www.thesgc.org/chemical-probes/GSK864).
Safety information for GSK990
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