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HomeProduct name listGSK255B)

GSK255B)

  • CAS NO.:1366233-41-1
  • Empirical Formula: C18H19ClFN3O3S
  • Molecular Weight: 411.88
  • MDL number: MFCD34469310
  • Update Date: 2025-04-18 09:51:54
GSK255B) Structural

What is GSK255B)?

Description

GSK 2332255B is a potent, and selective inhibitor of TRPC3/6 channels with IC50 of 3 nM/21 nM, respectively. It dispalys >100-fold selectivity over other calcium-permeable channels. It has 100-fold greater potency for TRPC3 compared with Pyr3. GSK 2332255B (dose-dependent) blocks cell hypertrophy signaling triggered by angiotensin II or endothelin-1 in HEK293T cells as well as in neonatal and adult cardiac myocytes.

Properties of GSK255B)

Boiling point: 542.7±60.0 °C(Predicted)
Density  1.417±0.06 g/cm3(Predicted)
pka 0.46±0.10(Predicted)

Safety information for GSK255B)

Computed Descriptors for GSK255B)

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