GNE-0723
- CAS NO.：1883518-31-7
- Empirical Formula: C16H8ClF6N5OS
- Molecular Weight: 467.78
- MDL number: MFCD30829912
- Update Date: 2026-04-21 10:31:43
What is GNE-0723?
The Uses of GNE-0723
EC50: 21 nM (GluN2A), 7.4 μM (GluN2C), 6.2 μM (GluN2D)
Biological Activity
GNE-0723 is a positive regulator of blood-brain barrier permeable NMDARs with EC50 values of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.
in vitro
GNE-0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC 50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.
Properties of GNE-0723
| Boiling point: | 505.2±60.0 °C(Predicted) |
| Density | 1.84±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | -0.82±0.70(Predicted) |
| color | White to yellow |
Safety information for GNE-0723
Computed Descriptors for GNE-0723
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