Gly-Gly-Leu
- CAS NO.：14857-82-0
- Empirical Formula: C10H19N3O4
- Molecular Weight: 245.28
- MDL number: MFCD00067447
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-21 14:05:29
What is Gly-Gly-Leu?
Chemical properties
White crystalline powder
The Uses of Gly-Gly-Leu
Gly-gly-leu is an oligopeptide, and also functions as a plant growth regulator.
Definition
ChEBI: Gly-Gly-Leu is a tripeptide composed of glycine, glycine and L-leucine residues joined in sequence. It has a role as a metabolite.
Synthesis
Glycylglycyl-L-leucine was prepared in 98% yield by hydrogenolysis of the protected tripeptide and crystallization of the product from aqueous ethanol. This matarial had [α]24D -28.4° (c, 2 in water), reported [α]20D -28. l° (c, 2.53 in water), [α]26D -28.0°, and [α]19D -29.9° (c, 2 in water)[1].
References
[1] Beechham A, et al. Residue rotations of L-leucine in the Di-, Tri-, Tetra-, and Penta-peptides of L-leucine and Glycine containing one L-leucyl residue. Australian Journal of Chemistry, 1967; 20: 1983 - 1989.
Properties of Gly-Gly-Leu
| Melting point: | 195-198 °C (decomp) |
| Boiling point: | 573.7±45.0 °C(Predicted) |
| Density | 1.199±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| pka | 3.35±0.10(Predicted) |
| InChI | InChI=1S/C10H19N3O4/c1-6(2)3-7(10(16)17)13-9(15)5-12-8(14)4-11/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,15)(H,16,17)/t7-/m0/s1 |
| CAS DataBase Reference | 14857-82-0(CAS DataBase Reference) |
Safety information for Gly-Gly-Leu
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H317:Sensitisation, Skin H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Gly-Gly-Leu
| InChIKey | XPJBQTCXPJNIFE-ZETCQYMHSA-N |
| SMILES | C(O)(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CN |
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